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SyroWave

 

Automated Microwave and Parallel Peptide Synthesizer

 

Biotage® Syro Wave™ is the only programmable peptide synthesizer that is capable of both conventional room temperature parallel peptide synthesis and microwave assisted peptide synthesis. The system is fully automated and computer controlled utilizing a pipetting robot with a single arm.

 

**Now available
with the new Syro Heating Block(s) option!

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Biotage® Syro Wave™ is a union of the MultiSynTech Syro I and Biotage Initiator instruments, controlled by a single PC. Syro Wave offers the unique ability to make part of the peptide sequence using conventional solid phase peptide synthesis on the parallel reactor block and then transfer the reactor vial to the microwave cavity to drive difficult couplings to completion. With the Syro Wave peptide synthesizer, Biotage offers a system with a proven pedigree and history of performance and reliability. The Syro XP software controls the instrument functions and calculates all amounts and volumes of amino acids and reagents required. Each cycle of the synthesis can receive a completely different protocol. This flexibility allows not only single or multiple couplings, but also complete freedom in the choice of coupling strategies within any synthesis cycle.

Biotage® Syro Wave™ is a programmable peptide synthesizer that is capable of both conventional room temperature parallel peptide synthesis and microwave assisted peptide synthesis. The system is a fully automated and computer controlled peptide synthesizer, based on a pipetting robot with a single arm.

The Biotage Syro Wave system is a combination of the MultiSynTech Syro I and Biotage Initiator 1 instruments, controlled by a single PC. This is the only system available with both microwave and parallel peptide synthesis capabilities. With the Syro Wave peptide synthesizer Biotage offers a system with a proven pedigree and history of performance and reliability.

Benefit from the unique ability to make part of the peptide sequence using conventional solid phase peptide synthesis on the parallel reactor block and then transfer the reactor vial to the microwave cavity to drive difficult couplings to completion.

 

 

  • System specification

    Spezification SyroWave

    Heating

    Microwave cavity

    Automation

    Automation

    Syringe pump

    Single 5 mL

    Reactor block

    U-type reactor block for 2, 5 and 10 mL reactor vials. Choice of

    Mixing

    Separate vortex mixers for reactor block and microwave cavity

    Vacuum pump

    ME 2C NT

    Amino acid rack

    32 x 50 mL Falcon tubes

    Reagent bottle rack

    2 x 500 mL, 3 x 200 mL

    Waste bottle

    1 x 10 liter Nalgene bottle

    Included equipment

    Desktop PC, flat panel monitor, printer and Syro XP software

    Dimensions (W x D x H)

    90 cm x 70 cm x 91 cm

    Weight

    85 kg

    Heating Process

    -

    Temperature range

    40–80 ºC

    Temperature increase

    Typically 2–5 ºC/sec

    Pressure range

    Run at atmospheric pressure

    Power range

    0–200 W at 2.45 GHz, capped at 60 W during steady state

    Agitation

    Vortex

    Reactor vial sizes

    Reactor vial sizes

    Microwave Unit Vial Volume Range

    2 mL reactor vial

    0.8–1.1 mL

    5 mL reactor vial

    1.6–3.2 mL

    10 mL reactor vial

    3.2–6.4 mL

    Power Requirements

    -

    Robot

    EU:       230 V~, 50 Hz        (6.1 A)
    USA:    120 V~,  60 Hz       (12.1 A)
    Japan:  100V ~,  50/60 Hz (13.5 A)

    Vacuum pump

    EU:           230 V~, 50/60 Hz (1.8 A)
    USA:        120 V~, 60 Hz       (3.4 A)
    Japan:      110 V~, 60 Hz       (3.4 A)

  • About SyroWave
    • Economically Synthesize Difficult Sequences
      Use microwave irradiation and standard reagents to synthesize difficult sequences that are problematic or even impossible to synthesize using standard methods.
       
    • Save Time and Increase Productivit
      Automated parallel operation allows for the synthesis of more peptides in shorter times resulting in the highest productivity. Reduce cycle times even further using microwave irradiation.
       
    • Increase Yield and Purity
      Accurate dispensing of exact volumes of all reactants and vortexing of the reaction mixture, guarantee the optimal result in terms of yield and purity while minimizing waste and costs.
       
    • Detailed Reagent Calculation
      The easy to use Syro XP software controls the instrument functions and calculates all amounts and volumes of amino acids and reagents required.
       
    • Reduce Coupling Costs
      The use of a digital syringe pump and minimized flow paths lead to low amino acid and reagent consumption. This reduces coupling and running costs compared to other systems.

     

  • Optional
    • Inert gas option
    • Inert gas cover plates
    • Disposable polypropylene reactor vials
    • Cleavage and Transfer Workstation
    • Standalone vortex mixer for cleavage unit
    • 24 and 48 position reactor blocks
    • Tip synthesis module for the synthesis of 96 peptides on 1–5 μmol scale
  • Consumables

    Item No.

    Discription

    S006VO002

    Vortex Mixer, Stand-Alone, Holds 2-Reactor Blocks Peptide synthesis

    S011TU024

    Transfer Unit 24 position

    S011TU048

    Transfer Unit 48 position

    S011TU424

    Transfer Unit 24- and 48 positions

    Z002BR024

    U-Block rack 24 position for 2 mL reactors

    Z002IC024

    Inert Gas Cover Plate, 24 x 2-mL reactor

    Z002IC048

    Inert Gas Cover Plate, 48 x 2-mL reactor

    Z004IC096

    Inert gas cover plate 96 pos.for Tip-reactors

    Z005BR024

    U-Block rack 24 position for 5 mL reactors

    Z005IC024

    Inert Gas Cover Plate, 24x5-mL reactors

    Z010IC024

    Inert Gas Cover Plate, 24x10-mL reactors

    Z024AK000

    Empty Head, 24-Position - Peptide synthesis

    Z024UB050

    U-Block Reactor, 24 x 2-5-10mL - Peptide synthesis

    Z048AK000

    Empty Head, 48-Position - Peptide synthesis

    Z048UB020

    U-Block Reactor, 48 x 2mL - Peptide synthesis

    Z102RF115

    Reagent brown glass bottle 200 ml for Syro I/Syro Wave with inert gas

    Z102RF127

    Reagent brown glass bottle 200 ml for Syro I/Syro Wave (no IG) or Syro II w/ IG

    Z102RF137

    Reagent brown glass bottle 200 ml for Syro II (no inert gas)

    Z105RF115

    Reagent brown glass bottle 500 ml for Syro I/Syro Wave with inert gas

    Z105RF127

    Reagent brown glass bottle 500 ml for Syro I/Syro Wave (no IG) or Syro II w/ IG

    Z105RF137

    Reagent brown glass bottle 500 ml for Syro II (no inert gas)

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